As men age, they may experience low energy, reduced libido, mood changes, and sleep issues, which are often linked to late-onset hypogonadism. While testosterone replacement therapy is a common treatment, it carries potential risks, including prostate-related concerns and cardiovascular complications, and may not be suitable for men with normal testosterone levels.1 In such cases, natural options like maca, a root native to the Andes and traditionally known as “Peruvian ginseng,” offer a promising alternative for supporting vitality and well-being.
The Study
A randomized, double-blind clinical trial in Korea set out to explore the efficacy and safety of gelatinized maca in men with normal testosterone levels experiencing late-onset hypogonadism symptoms. The results were published in the World Journal of Men's Health.
Eighty participants were assigned to take either maca or a placebo, for 12 weeks before meals. Researchers evaluated symptom changes using a variety of tools. Blood tests and physical metrics like body weight and waist circumference were also measured.
The Results
By week 12, men who took maca reported significant improvements in overall well-being, especially in symptoms linked to age-related hormonal decline.
Sexual function improved in the maca group but worsened in the placebo group. Fewer maca users showed signs of low androgen activity, and many also experienced better urinary health.
Importantly, these benefits occurred without major changes in testosterone levels or serious side effects. Only a few reported mild stomach discomfort, and no participants withdrew from the study.
What Does this Mean?
This trial demonstrates that maca helps relieve symptoms of late-onset hypogonadism, such as low energy, vitality loss, and reduced sexual function, without altering hormone levels. Instead, maca appears to support the body in a more balanced way, helping men regain vitality and well-being often diminished with age.
Other plant-based options, including ashwagandha, ginseng, and fenugreek, are also being studied as safe, effective tools for maintaining men's health.
Sources
- The World Journal of Men's Health, Efficacy and Safety of Maca (Lepidium meyenii) in Patients with Symptoms of Late-Onset Hypogonadism: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial , 2023
Footnotes:
- Mayo Clinic. (2024). Testosterone therapy: Potential benefits and risk as you age. Retrieved March 28, 2025, from https://www.mayoclinic.org/healthy-lifestyle/sexual-health/in-depth/testosterone-therapy/art-20045728







